The mean settling velocities of suspended sediments in turbulence have been examined. The settling velocities in a flume are directly measured by using an acoustic Doppler velocimeter. The results indicate the same trend as previous work in homogeneous isotropic turbulence. In addition to the flume experiment, the numerical experiments were conducted in the velocity field of homogeneous isotropic turbulence simulated by Kraichnan’s technique. The experimental and numerical results show that at high turbulence intensity the relative settling velocity increases with the increasing relative turbulence intensity regardless of the Stokes number. At intermediate turbulence intensity, it seems that the settling data bifurcate, i.e., the particles at the large Stokes number tend to be slowed, whereas the settling velocity of particles is increased at the small Stokes number.